Definition
Clinical syndrome characterised by
Synovitis
Acne
Pustulosis
Hyperostosis
Osteitis
Aetiology
Unknown
- high prevalence of HLA B-27 antigen
- similarities to seronegative spondyloarthropathy
Four types
1. Severe acne or hidradenitis suppuritiva with osteoarticular disease
2. Palmoplantar pustulosis with osteoarticular disease
3. Axial or appendicular hyperostosis +/- pustular dermatosis (sternocalvicular hyperostosis)
4. Disease similar to CRMO
Symptoms
Sternoclavicular hyperostosis
Sterile inflammatory lesions
Hyperostosis & osteitic lesions may be similar to malignant conditions
Synovitis does not usually lead to bony erosions
Management
Analgesics & oral anti-inflammatories
Prognosis
Favourable
- often protracted course with intermittent relapses & remissions without serious disability