bone scans

Technetium 99m labelled MDP (Mono - diphosphonate)

1. Pure gamma emitter

2. Half life only 6 hours

- limits radiation exposure

3. Localises in bone

- chemical interaction on the surface of the hydroxyapatite crystal of bone

- phosphorous component interacts with the endogenous calcium

- produces insoluble technetium calcium phosphate complexes.