spondylosis

Ochronosis

Degenerative arthropathy due to Alkaptonuria

Rare hereditary disorder of tyrosine and phenylalanine breakdown

Homogentisic acid enzyme deficiency

- accumulate Homogentisic Acid

- product of tyrosine breakdown

Homogentisic acid deposited in cartilage & other soft tissues

- polymerises

Cervical spondylosis

- chronic disc degeneration & associated facet arthropathy

Cervical myelopathy

- spinal cord dysfunction

- secondary to extrinsic compression of cord or its vascular supply

Cervical radiculopathy

- sclerotomal distribution of motor &/or sensory symptoms or signs

- due to compression of nerve root