staging
Approach to Primary Bone Tumour
Steps
1. Establish a differential
2. Stage locally and systemically
3. Biopsy
4. Definitive Treatment
1. Establish a Differential
Lesion detected on X-ray
Questions
- what do you think it is?
Principles of Soft Tissue Sarcoma
Most common sarcomas
1. MFH
2. Liposarcoma
3. Rhabdomyosarcoma (Paediatric)
4. Synovial Sarcoma
5. Leiomyosarcoma
6. Fibrosarcoma
Ten Tissues of Origin
1. Adipose / LS
2 Fibrous / FS
3. Fibrohistiocytic / MFH
Ewing Sarcoma
Principles
Treatment algorithm similar to OS
Overall prognosis similar to OS
- 70% long term survival
Definition
A malignant neoplasm composed of small round cells of uncertain histogenesis
Genetics
Recent data suggests it is of neuroepithelial derivation
- ? neuroectodermal cells