Undifferentiated Pleomorphic Sarcoma
Definition
Malignant Fibrous Histiocytoma
Characterised by heterogenous population of pleomorphic spindle cells
- organised in a characteristic storiform or "starry night" pattern
Cell of origin unknown
- primitive mesenchymal cell
- allowing both features of a macrophage (hence histiocyte)
- and collagen producing cell (hence fibroblast)
Epidemiology