clinical

Definition

Disseminated Intravascular Coagulation

Pathology

Results from excessive activation of either extrinsic or intrinsic coagulation pathway

- multiple small clots 

- consumptive coagulopathy

1.  Excessive Extrinsic Activation

Secondary to extensive cellular destruction

- thromboplastins +++ released into circulation

Definition

Definition

STS composed of malignant lipoblasts

Epidemiology

Common 

- 10% of STS

- second only to MFH

Occurs almost exclusively in adults

Males age 40-60

Can be multiple origin -> examine patient

Rarely arise from lipoma