treatment algorithm

Management

NHx

 

European Orthopaedic Paediatric Study JPO 1999

- 452 patients

- juvenile and adult

 

Findings

- stable lesion with cartilage intact and no dissection had good prognosis

- if signs dissection, surgical management better than non surgical

- sclerosis on x-ray poor prognostic sign

- lesions > 2cm poor prognosis

- 20% OCD in juveniles abnormal x-ray findings at 3 years (not benign process)

Ewing Sarcoma

Principles

 

Treatment algorithm similar to OS

 

Overall prognosis similar to OS

- 70% long term survival

 

Definition

 

A malignant neoplasm composed of small round cells of uncertain histogenesis

 

Genetics

 

Recent data suggests it is of neuroepithelial derivation

- ? neuroectodermal cells