SLE

Inflammatory Arthritis

Acro-osteolysis

SLE

Scleroderma

Psoriasis

Definition

Absorption of distal tuft of phalanx

DDx

Psoriasis

Scleroderma / Raynauds

Frost Bite

Hyperparathyroidism

Diabetes

Vasculitis

Leprosy

RA rarely

Gout

Systemic Connective Tissue Disease

Chronic inflammatory disease resulting from abnormal immunoregulation

Unknown

Thought similar to RA

1. Genetic factors

2. Environmental factors

Young females

F:M 9:1

Peak 35 years old