large vessel disease

Background

Diabetic Foot Pathophysiology 

 

1. Neuropathy

2. Arteriopathy

3. Immunopathy

 

Neuropathy 

 

Most important aetiologic factor in foot disease. Due to : 

- metabolic (glycosylation of nerves)

- ischaemic factors 

 

A.  Sensory Neuropathy

 

Definition