Multiple Hereditary Exostosis
AKA
Diaphyseal Aclasis / Multiple Osteochondromas
Definition
Heritable skeletal dysplasia
Epidemiology
AD with variable penetrance (96%)
Malignant Transformation
Incidence of malignant transformation much higher
- 10% overall
- 1 % / year
Chondrosarcoma (CS) > Osteosarcoma (OS)