BMP

Non Union

Non-union

- arrest of progression to union at fracture site

- > 6-9 /12

- no visible progressive signs of healing for at least three consecutive months

- individualise for each fracture

- when the surgeon believes the fracture has little or no chance to heal

Delayed union

- failure of fracture to unite within expected time

- still may spontaneously unite

Bone healing requires 3 things

- osteoconduction - scaffold / matrix

- osteoinduction - growth factors

- osteogenesis - cells to produce osteoid

Definition

- property of a matrix that supports the attachment of bone forming cells for subsequent bone formation

Substances